Tuesday, January 31, 2023

Can Stress Cause Liver Damage

Underlying Conditions That May Cause Irregular Heartbeats

Can Gluten Cause Liver Damage? Yes – Here are three examples

In many cases, there is nothing inherently wrong with the heart. Instead, an underlying issue is causing disturbances in the hearts rhythm. Here are a few examples:

  • Thyroid disease: Thyroid disease impacts the levels of hormones in your blood, which can disrupt the normal electrical pattern that triggers heartbeats.
  • High blood pressure: Having chronically high blood pressure puts stress on your blood vessels and your heart muscle, which can increase the risk of experiencing heart palpitations.

Treatment And General Recommendations

  • If possible, take practical steps to change or resolve a stressful situation. For example, seek relationship counselling speak to a supervisor or mediator at work about changing work practises or resolving a personality conflict offload some of your responsibilities at home or work cut down from full time to part time work discuss money problems with a financial planner or bank manager.
  • Some of you may need to re-educate your thinking to realize that you are not indispensable that others can carry out some of your tasks quite adequately even if not in exactly the same way as you, and that things like a perfectly spic and span house are not really important in the big scheme of things. However, it is worth trying to be organized so that you are not getting stressed about running late for an appointment or forgetting to do something important.
  • Relaxation exercises, yoga or meditation are great stress relievers. Regular physical exercise like going for a brisk walk is also highly beneficial to burn up those stress hormones and improve your feeling of general wellbeing.
  • Having a hobby or taking time out for yourself to do something relaxing like soaking in a bubble bath or having a therapeutic massage is another good way of releasing pent-up tensions.
  • Many people have found that acupuncture is helpful.

Alcohol Or Drug Use Disorder

Drinking too much alcohol or using illicit drugs may lead to liver inflammation or damage.

Liver inflammation due to alcohol consumption is called alcoholic hepatitis. When drugs are the underlying cause, doctors call it toxic hepatitis.

The symptoms of alcoholic and toxic hepatitis are similar to those of other strains of hepatitis.

If a person is experiencing symptoms of alcohol or drug use disorder, the doctor may check their liver enzyme levels and offer various forms of treatment and support.

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Baseline Characteristics Of The Study Population

Among the total of 25,333 subjects, the mean age was 47 years, and men comprised 56.2%. The prevalence rate of NAFLD was 30.9%. The subjects with NAFLD were divided into three groups based on their ultrasonographic findings of steatosis. To rule out the effects of gender, we stratified the population according to gender. The baseline characteristics of the male participants are shown in Table 1. NAFLD was more frequently observed in people who were older and smokers. Prevalence of diabetes was significantly higher in subjects with NAFLD. In addition, most of the anthropometric and laboratory variables were less metabolically favorable in subjects with NAFLD . The prevalence rates of depression and anxiety were not significantly different in the NAFLD and control groups.

Table 1. Comparison of baseline characteristics according to nonalcoholic fatty liver disease in males.

In the female group, NAFLD was more frequently observed in people who were older and never-smokers. Other baseline characteristics were almost similar to those of men except for the prevalence rates of depression which was higher in the NAFLD group compared to the control group . Figure 2 shows the scores of depression according to the stage of steatosis. The BDI score was significantly higher in the severe NAFLD group compared to the no-NAFLD group . The effect sizes of the differences were provided in the Supplementary Table 1.

Heart Conditions That Cause Palpitations

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As mentioned above, heart palpitations may occur for absolutely no reason. But they may also occur because of a heart condition, specifically a condition that affects the heart rhythm.

Stress and anxiety may also worsen heart conditions if you have one, and trigger symptoms. Again, keep in mind that many of these conditions are absolutely harmless and/or can be treated. Lets get into these conditions that can cause disturbances in heart rhythm.

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Road To Diagnosis And Treatment

Leading up to her diagnosis, Sarata felt lethargic, bloated, began gaining weight, and became forgetful, all which worsened over a 3-year span after her diagnosis.

Bajaj says HE can cause a spectrum of brain function changes ranging from subclinical feeling of slowing all the way to coma.

All these stages have their unique challenges. Covert HE can often be felt by patients by the feeling of slowing down in general and specifically during work and driving and changes in sleeping pattern. Overt episodes often present with confusion, not knowing where one is or is doing and personality changes, Bajaj told Healthline.

Saratas symptoms affected her to the point where she could no longer work at her job as a medical sales representative.

I couldnt be responsible enough to get to where I was going. I had to drive a lot, but I would get lost all the time. I had many instances where I was supposed to be in a doctors office in one city and went to another city instead, she said.

Her social life and relationships were also impacted.

The most heartbreaking incident she recalls is kicking her mother out of her house because she believed she was an intruder pretending to be her mom.

Fear of interacting caused her to have social anxiety.

After diagnosis, she ended up in the emergency room monthly, and at one point, she was in a coma for 13 days due to uncontrolled HE.

My ex-husband found me on the ground foaming at the mouth, she said.

How Stress Affects Your Liver Health

Whats in this article

  • What is stress?
  • How to tell if you are stressed
  • How stress affects your liver health
  • Effective Management

What is stress?Stress is not good for our bodies, it can lead to many physical and mental health issues, but what exactly is it? It is our bodies reaction to a situation that the body deems harmful. Without stress the human race would not have survived, going back to caveman times, it was what alerted our ancestors of potential dangers. Fast forward to today and we still have that fight or flight mode built into us. When we get stressed, our body releases a mixture of hormones and chemicals such as adrenaline, cortisol and norepinephrine. This causes the body to have different responses such as blood being diverted to muscles or shutting down our digestion. It is easy to see that over time stress can really take a toll on our health.

How to tell if you are stressedWe all handle stress in different ways and so symptoms are broad. Stress can mimic symptoms of many health conditions so it is important to talk to your doctor about any changes with your mind and body.

  • Get giggling laughing is an effective stress buster
  • Work on spoiling yourself with hobbies, massages, treatments etc.
  • Surround yourself with positive people and attitudes

Find out about the nutrition bar that 98% of liver health experts would recommend!




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See Your Doctor Regularly

Seeing your doctor on a regular basis is important for your overall health. Your doctor can help identify and treat any underlying health conditions early on, before they become more serious or complicated.

Also, if you notice any early signs of liver damage, be sure to make an appointment with your doctor or healthcare provider. They can help evaluate your condition and outline a treatment plan to ensure your liver gets the rest and treatment it needs.

Can Stress Raise Liver Enzymes

Can stress cause fatty liver?

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Cortisol Stress Hormone And Fatty Liver

In other research it was found that cortisol the stress hormone could increase the risk of a fatty liver. The study, published in Clinical Endocrinology, found a link between cortisol levels in men and fatty liver disease. Fatty liver disease occurs when too much fat forms around or in the liver, thus negatively affecting the livers function.

Researchers found those with non-alcoholic fatty liver disease had an overproduction of cortisol. Researchers believe that overproduction of cortisol is what contributes to the excess fat in the liver as cortisol is known to promote fat deposits in the liver.

Excessive cortisol is not only harmful for the liver, but it can wreak havoc on your body and overall health. Researchers suggest that if high cortisol levels can contribute to fatty liver, lowering cortisol can diminish fatty liver.

Eating Plenty Of Fiber

Fiber is extremely important for supporting heart health. Foods that are high in fiber, such as oat bran, wheat bran, and other whole-grain products, help lower inflammation throughout the body. One way that they do this is by supporting a healthy balance of gut flora in the microbiome. When we eat fiber, fiber particles travel through the digestive tract and into the intestines relatively intact. In the intestines good gut bacteria break down and feed on the fiber, producing anti-inflammatory compounds as by-products. These anti-inflammatory compounds are then absorbed through the intestinal wall and into the bloodstream where they can then circulate through the bloodstream and reduce inflammation. Eating a diet high in fiber is associated with lower cholesterol levels and a lower risk of developing heart disease.

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Chronic Vs Acute Liver Disease

Dogs may be susceptible to two different types of liver disease: chronic liver disease and acute liver failure. Chronic liver disease occurs gradually over time. This form of disease is often a result of ongoing damage caused by another chronic health problem. Normal wear and tear on the body can result in liver disease in your pets old age, while conditions like cancer can put undue stress on the liver.

Acute liver failure, on the other hand, occurs suddenly and often without warning. In most cases, acute liver failure is a direct result of poisoningwhen your dog ingests a large quantity of toxic material that the liver cant effectively process. Liver trauma can also cause acute liver failure.

With chronic liver disease, the condition can often be managed with a treatment plan you devise with your veterinarian. These treatments might include dietary changes, medications and supplements to support liver function and keep your pups body working as long as possible.

Unfortunately, treatment is much more difficult in the case of acute liver disease. Dogs experiencing a rapid decline in liver function must be seen by a vet immediately. Waiting too long to seek help could result in total liver failure and death.

Physiology And Interactions With Immune

Liver function and dysfunction â a unique window into the ...

The HPA axis and the systemic sympathetic and adrenomedullary system are the key components of the stress system. Their main function is to maintain basal and stress-related homeostasis. They respond to several signaling molecules, such as cytokines produced by immune-mediated inflammatory reactions, tumor necrosis factor -, interleukin-1 , and interleukin-6 .

Corticotrophin-releasing hormone and noradrenergic neurons of the central stress system innervate and stimulate each other. By using specific receptors, CRH stimulates norepinephrine secretion, while in turn norepinephrine stimulates CRH secretion primarily through 1-noradrenergic receptors. An ultrashort negative-feedback loop also exists for both CRH and norepinephrine, down-regulating their production. The serotonergic and cholinergic systems stimulate CRH, arginine vasopressin , and noradrenergic neurons whilst being inhibited by the opioid-peptide and -aminobutyric acid-benzodiazepine systems existing in the brain. Hypothalamic CRH neurons are inhibited by centrally secreted substance P while AVP neurons remain unaffected. Substance P also stimulates the central noradrenergic system.

All key hormones secreted by HPA components play different roles in the modulation of the immune response and the development of the inflammatory reaction.

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The Stages Of Hepatic Encephalopathy

The stages of hepatic encephalopathy are graded on a scale called the West Haven Criteria, which classifies the severity of symptoms based on the level of neurological impairment:

  • Minimal: changes in motor speed without signs of mental changes
  • Grade 1: trivial lack of awareness, euphoria or anxiety, shortened attention span, altered sleep rhythm
  • Grade 2: lethargy or apathy, disorientation, obvious personality change, inappropriate behavior, motor skill problems, tremors with “flapping” of hands
  • Grade 3: a semi-stupor state, confusion, severe disorientation, bizarre behavior
  • Grade 4: coma

Clinical diagnoses are also made by classifying the underlying cause, whether it be an acute liver failure , a portosystemic shunt that bypasses the liver , or cirrhosis . Each of these classifications assists in determining the appropriate course of action in treating the condition.

How Liver Failure Affects The Brain

Hepatic encephalopathy typically occurs when the liver is no longer able to perform its usual metabolic functions.

In persons with a normal liver function, nitrogen-containing compounds from the intestines are transported to the liver, where they are processed and excreted from the body. When liver function is impaired, the nitrogen-containing compounds begin to gradually build up, which causes an increase in ammonia levels.

These ammonia particles then spread throughout the bloodstream and pass through the semi-permeable membrane that that surrounds the brain. There, they cause the swelling of brain cells called astrocytes, which eventually slows the production of neurotransmitters vital to cognitive thinking.

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Stress And Chronic Hepatitis

Numerous studies also point to the association between stress, more specifically psychosocial stress, and the development of viral hepatitis. In one study researchers found a link between psychosocial stress and the severity of chronic hepatitis C. In individuals with low self control, object dependence of loss, unfulfilled need for acceptance and altruisms , researchers found more susceptibility to psychosocial stress, which was linked to hepatitis C severity.

Other studies have found that psychosocial stress affects antibody response after a hepatitis B vaccination. One survey revealed that those with higher responses that indicated stress also had weakened immune responses when they received the vaccination.

When To Seek Medical Attention

Liver Disease and Anxiety and Depression – Liver Disease in the News

Though palpitations are extremely common and in most cases not serious, its probably still a good idea to get them checked out by a doctor, even if only for peace of mind. If your heart palpitations are new and increasing in frequency, its probably best to be evaluated by a physician, just to determine the cause and whether you need treatment.

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Foods To Eat Or Avoid

  • Consuming high amount of processed foods, which are often loaded with preservatives, additives, artificial sweeteners and flavorings expose the liver to damage because they are very hard to break down as they are full of chemicals. Read my article about the top 10 worst ingredients in food, and youll realize that some of the common ingredients found in processed foods can be harmful for your health.
  • Processed foods are also high in salt, which is not only known to increase blood pressure, but can also cause fatty liver disease by building up fluid in the liver and swelling.
  • Not eating enough fruits, leafy greens and other vegetables which are all great sources of antioxidants, will not give the body enough beta-carotene, vitamin C and E, zinc and selenium which all help keep the liver healthy.
  • Vitamin B12, mainly available in meat, is used by the liver to help with the flow of bile, so make sure you dont have vitamin b12 deficiency. Other B vitamins aid in liver detoxification, and can be found in nuts, egg yolks, poultry, fish, legumes and brown rice.
  • Other important nutrients that help the liver include lecithin and sulphur. Lecithin helps the liver get rid of excess fat. Good sources of lecithin include egg yolks, legumes, wheatgerm and fish. Sulphur, which helps to detoxify the liver, is found in fish and lean meat, eggs, cauliflower, broccoli, cabbage, turnips, onions, leeks, garlic and dried legumes.

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When Are Heart Palpitations Not Normal

If your heart is palpitating and you are also experiencing shortness of breath, fainting, chest pain, a prolonged and continuous period of irregular heartbeats, or any other concerning symptoms, seek medical attention immediately. These symptoms may indicate heart attack, heart failure, or other serious heart problems.

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Liver Dysfunction Due To Toxicity

In the 21st century, I think it would be fair to say that liver dysfunction is pandemic. It is extremely rare to find a person whose liver is not suffering from some toxicity and that, I’m afraid to say, is entirely down the way that we live these days.

There could be several different contributing factors :

But to understand how liver damage symptoms can rear their heads in every day conditions such as eczema and migraine, I think that it is worth just asking what does the liver do? Once you understand it’s functions it is easier to see how things start to go wrong.


Stress And Liver Cirrhosis

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Psychosocial stress per se may exaggerate inflammatory and fibrosing change in the cirrhotic liver.

Nagano et al included in their clinical test a subset of patients affected by cirrhosis. They found the same positive correlation between psychosocial stress and liver injury, as ALAT values strongly correlated with high stress scores in the cirrhosis cohort.

Tanaka et al conducted a long-term follow-up study determining risk factors for malignant transformation of cirrhotic lesions in Japanese patients. His study also demonstrated a possible link between the presence of stress and precipitating indicators for cirrhosis.

Several animal studies were conducted, outlining important cellular mechanisms that link stress response of the sympathetic nervous system, as well as alterations of the HPA axis responsiveness, with liver inflammation in cirrhosis.

Electric foot shock stress exacerbated liver injury in rats treated with carbon tetrachloride. Alterations of the HPA axis responsiveness, as well as elevated plasma cytokine levels, accompany experimental chronic liver disease in mice. Elevated TNF- and IL-6 levels, coupled with liver injury, decrease hypothalamic mRNA and protein expression of CRH. When mice are exposed to psychological stress, HPA axis functions abnormally, suffering defective activation and significant attenuation in the resultant release of GCs, compared to control groups.

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